3 research outputs found
Mixture Flash Point Calculation: Recent Advances and a Closer Look at Biodiesel
To safely handle, transport, and store flammable or combustible
liquids, such as biodiesel and its blends, it is important to have
knowledge of a few physical-chemical properties. The Flash Point is
an important one, as it is related to the flammability of the fuel
blend. It can be experimentally measured through open cup or closed
cup standard procedures. However, due to the usual scarcity of experimental
data for multicomponent systems, developing a model to predict flash
points of mixtures is of interest. To do so, there are a few possible
approaches, which include empirical regression of data, vapor pressure-based
methods, and QSPR. When it comes to mixtures, the most popular modeling
method is based on vapor pressure, which usually employs LeChatelier’s
rule and vapor–liquid equilibria (VLE) calculations to flash
point prediction. Generally, a γ–φ approach is
adopted to describe the VLE behavior, although some authors have shown
interest in φ–φ approaches. In recent years, studies
on QSPR for FP prediction of mixtures have evolved, which represents
an advance toward more generalized FP prediction models. Additionally,
COSMO type models have been gaining attention in FP prediction, usually
associated with vapor pressure models or even empirical models. When
it comes to biodiesel though, not much progress has been made since
2014, with just a few works being published since then. This paper
seeks to review advances made in FP prediction methods for mixtures
in general, while giving attention to those involving biodiesel and
petro-diesel
Microfluidic Fabrication of Pluronic Vesicles with Controlled Permeability
Block copolymers with a low hydrophilic-to-lipophilic
balance form
membranes that are highly permeable to hydrophilic molecules. Polymersomes
with this type of membrane enable the controllable release of molecules
without membrane rupture. However, these polymersomes are difficult
to assemble because of their low hydrophobicity. Here, we report a
microfluidic approach to the production of these polymersomes using
double-emulsion drops with ultrathin shells as templates. The small
thickness of the middle oil phase enables the attraction of the hydrophobic
blocks of the polymers adsorbed at each of the oil/water interfaces
of the double emulsions; this results in the dewetting of the oil
from the surface of the innermost water drops of the double emulsions
and the ultimate formation of the polymersome. This approach to polymersome
fabrication enables control of the vesicle size and results in the
efficient encapsulation of hydrophilic ingredients that can be released
through the polymer membrane without membrane rupture. We apply our
approach to the fabrication of Pluronic L121 vesicles and characterize
the permeability of their membranes. Furthermore, we show that membrane
permeability can be tuned by blending different Pluronic polymers.
Our work thus describes a route to producing Pluronic vesicles that
are useful for the controlled release of hydrophilic ingredients